{"id":11654,"date":"2025-07-31T09:00:27","date_gmt":"2025-07-31T00:00:27","guid":{"rendered":"https:\/\/blog.agentsoft.co.kr\/index.php\/2025\/07\/31\/11654\/"},"modified":"2025-07-31T09:00:27","modified_gmt":"2025-07-31T00:00:27","slug":"%eb%a9%b4%ec%97%ad%ec%a1%b0%ec%a7%81%ed%99%94%ed%95%99%eb%b2%95%ec%9d%84-%ec%9d%b4%ec%9a%a9%ed%95%9c-rat-brain%ec%9d%98-neuron-%ea%b4%80%ec%b0%b0%ea%b3%bc-%ed%95%ad%ec%95%94%ec%a0%9c-taxol%ea%b3%bc-ci","status":"publish","type":"post","link":"https:\/\/blog.agentsoft.co.kr\/index.php\/2025\/07\/31\/11654\/","title":{"rendered":"\uba74\uc5ed\uc870\uc9c1\ud654\ud559\ubc95\uc744 \uc774\uc6a9\ud55c Rat brain\uc758 Neuron \uad00\ucc30\uacfc \ud56d\uc554\uc81c Taxol\uacfc Cisplatin\uc758 \ub09c\uc18c\uc554\uc138\ud3ec(SKOV3 cell line)\uc5d0\uc11c\uc758 \ubbfc\uac10\ub3c4 \uce21\uc815"},"content":{"rendered":"

<\/p>\n

\ubaa9\ucc28<\/strong><\/p>\n

\u2160. \uc11c\ub860<\/p>\n

\u2161. \uc774\ub860
\n 1. \ub09c\uc18c\uc554
\n 2. Immunohistoch emistry(\uba74\uc5ed \uc870\uc9c1 \ud654\ud559)
\n 3. \ub3d9\ubb3c\uc138\ud3ec\ubc30\uc591
\n 4. MTT (Thiazolyl Blue Tetrazolium Bromide) Assay
\n 5. Apoptosis<\/p>\n

\u2162. \uc2e4\ud5d8\ub3c4\uad6c \ubc0f \uc7ac\ub8cc<\/p>\n

\u2163. \uc2e4\ud5d8\ubc29\ubc95<\/p>\n

\u2164. \uacb0\uacfc<\/p>\n

\u2165. \uace0\ucc30<\/p>\n

\u2166. \ucc38\uace0\ubb38\ud5cc<\/p>\n

\ubcf8\ubb38\ub0b4\uc6a9<\/strong><\/p>\n

\ub09c\uc18c\uc554\uc740 \uc5ec\uc131\uc0dd\uc2dd\uae30\uc5d0 \ubc1c\uc0dd\ud558\ub294 \uc554 \uac00\uc6b4\ub370 \ud55c\uad6d \uc5ec\uc131\uc758 \uacbd\uc6b0 \uc790\uad81\uacbd\ubd80\uc554 \ub2e4\uc74c\uc73c\ub85c \ubc1c\uc0dd\ube48\ub3c4\uac00 \ub192\ub2e4. \uad6d\ub0b4\uc5d0\uc11c\ub294 \uc5ec\uc131 \uc554\uc758 2.8%\uc815\ub3c4\ub97c \ucc28\uc9c0\ud558\uace0 \uc788\uc73c\uba70 \uc790\uad81\uacbd\ubd80\uc554\uc758 \uacbd\uc6b0\ub294 \uc810\ucc28\ub85c \uac10\uc18c\ud558\ub294\ub370 \ube44\ud558\uc5ec \ub09c\uc18c\uc554\uc740 \uc810\ucc28\ub85c \uc99d\uac00\ud558\ub294 \ucd94\uc138\ub97c \ubcf4\uc774\uace0 \uc788\ub2e4. \uc790\uad81\uacbd\ubd80\uc554\uc758 \uacbd\uc6b0\uc5d0 \uc788\uc5b4\uc11c\ub294 \uc870\uae30 \uc9c4\ub2e8\uc5d0 \ub530\ub978 \uc0ac\ub9dd\ub960\uc758 \uac10\uc18c\ub97c \ubcf4\uc774\ub294\ub370 \ubc18\ud558\uc5ec \ub09c\uc18c\uc554\uc740 \uc870\uae30 \uc9c4\ub2e8\uc774 \uc6a9\uc774\ud558\uc9c0 \uc54a\uc544 2\/3\uc758 \ud658\uc790\uc5d0\uc11c\ub294 \uc774\ubbf8 \uc9c4\ud589\uc131 \uc554\uc73c\ub85c \ubc1c\uacac\ub418\ubbc0\ub85c \uc218\uc220 \ubc0f \ubcf4\uc870\uc801 \uce58\ub8cc\uc758 \uac1c\uc120\uc5d0\ub3c4 \ubd88\uad6c\ud558\uace0 \ub09c\uc18c\uc554\uc73c\ub85c \uc778\ud55c \uc0ac\ub9dd\ub960\uc5d0\ub294 \ud070 \ubcc0\ud654\uac00 \uc5c6\ub294 \uc2e4\uc815\uc774\ub2e4.
\n \ub09c\uc18c\uc554 \ud658\uc790\uc758 \uc0dd\uc874\uc728\uc744 \ub192\uc774\uae30 \uc704\ud574 \ub9ce\uc740 \ud56d\uc554\uc81c\ub4e4\uc774 \uac1c\ubc1c\ub418\uc5b4 \uc0ac\uc6a9\ub428\uc73c\ub85c\uc11c \uc0dd\uc874\uc728\uc740 \uc870\uae08\uc529 \ub098\uc544\uc9c0\uace0 \uc788\uc9c0\ub9cc \ubcd1\uae30\uac00 3\uae30 \uc774\uc0c1\uc778 \uacbd\uc6b0 \uc0dd\uc874\uc728\uc740 11-41%\ub85c \uc544\uc9c1\ub3c4 \uc5ec\uc131\uc554 \uc911\uc5d0\uc11c \uac00\uc7a5 \uce58\uba85\uc801\uc778 \uc554\uc778 \uac83\uc774 \ud604\uc2e4\uc774\ub2e4. \ub09c\uc18c\uc554 \uce58\ub8cc\uc758 \ud56d\uc554\uc81c\ub85c 1990\ub144 \uc774\uc804\uc5d0\ub294 melphalan, cyclophospamide, doxorubicin, cisplatin \ub4f1\uc774 \uc0ac\uc6a9\ub418\uc5c8\ub294\ub370 \ub2e8\ub3c5 \uc694\ubc95\ubcf4\ub2e4\ub294 platinum\uc81c\uc81c\ub97c \uae30\ubcf8\uc73c\ub85c \ud55c \ubcd1\uc6a9 \uc694\ubc95\uc758 \ud6a8\uacfc\uac00 \ub354 \uc88b\uc544\uc11c doxorubicin, cisplatin \ub610\ub294 cyclophospamide, cisplatin \ub4f1\uc758 \ubcd1\uc6a9 \uc694\ubc95\uc774 \uc0ac\uc6a9\ub418\uc5b4 \uc654\ub2e4. 1990\ub144\ub300 \ucd08\uc5d0 taxene\uacc4\uc5f4\uc758 paclitaxel\uc774 \ub09c\uc18c\uc554 \uce58\ub8cc\uc5d0 \ub3c4\uc785\ub418\uba74\uc11c \uadf8 \ub6f0\uc5b4\ub09c \ud6a8\uacfc\ub85c \uc778\ud574 \ud604\uc7ac \ub09c\uc18c\uc554\uc758 \ud56d\uc554\ud654\ud559\uc694\ubc95\uc758 \uc77c\ucc28\uce58\ub8cc\uc694\ubc95\uc73c\ub85c paclitaxel\uacfc platinum\uc758 \ubcd1\uc6a9 \uc694\ubc95\uc774 \uac00\uc7a5 \ub9ce\uc774 \uc0ac\uc6a9\ub418\uace0 \uc788\ub2e4.
\n\uba74\uc5ed\uc870\uc9c1\ud654\ud559\ubc95\uc774\ub780 \ud56d\uc6d0\ud56d\uccb4\ubc18\uc751\uc758 \uc608\ubbfc\uc131\uacfc \ud2b9\uc774\uc131\uc744 \uc774\uc6a9\ud574 \ud2b9\uc815 \ub2e8\ubc31\uc9c8\uc5d0 \ub300\ud55c \uc0dd\uc131\ubb3c\uc9c8\uc744 \uac80\ucd9c\ud558\ub294 \ubc29\ubc95\uc73c\ub85c \uc870\uc9c1\uc758 \uc5b4\ub5a4 \ubd80\uc704\uc5d0\uc11c \ub2e8\ubc31\uc9c8\uc774 \ubc1c\ud604\ub418\ub294\uac00\ub97c \uc815\ud655\ud788 \uc721\uc548\uc73c\ub85c \uad00\ucc30\ud558\ub294 \uc77c\uc885\uc758 \ubd84\uc11d\uac80\uc0ac\ub77c\uace0 \ud560 \uc218 \uc788\ub2e4. \uc870\uc9c1 \ud56d\uc6d0 (tissue antigen) \uc5d0 primary antibody\ub97c \uacb0\ud569\uc2dc\ud0a4\uace0 primary antibody\uc5d0 secondary linking antibody\ub97c \ubd99\uc5ec \ubcf8\ub2e4.<\/p>\n

\ucd9c\ucc98 : \ud574\ud53c\ucea0\ud37c\uc2a4<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

\ubaa9\ucc28 \u2160. \uc11c\ub860 \u2161. \uc774\ub860 1. \ub09c\uc18c\uc554 2. Immunohistoch emistry(\uba74\uc5ed \uc870\uc9c1 \ud654\ud559) 3. \ub3d9\ubb3c\uc138\ud3ec\ubc30\uc591 4. MTT (Thiazolyl Blue Tetrazolium Bromide) Assay 5. Apoptosis \u2162. \uc2e4\ud5d8\ub3c4\uad6c \ubc0f \uc7ac\ub8cc \u2163. \uc2e4\ud5d8\ubc29\ubc95 \u2164. \uacb0\uacfc \u2165. \uace0\ucc30 \u2166. \ucc38\uace0\ubb38\ud5cc \ubcf8\ubb38\ub0b4\uc6a9 \ub09c\uc18c\uc554\uc740 \uc5ec\uc131\uc0dd\uc2dd\uae30\uc5d0 \ubc1c\uc0dd\ud558\ub294 \uc554 \uac00\uc6b4\ub370 \ud55c\uad6d \uc5ec\uc131\uc758 \uacbd\uc6b0 \uc790\uad81\uacbd\ubd80\uc554 \ub2e4\uc74c\uc73c\ub85c \ubc1c\uc0dd\ube48\ub3c4\uac00 \ub192\ub2e4. \uad6d\ub0b4\uc5d0\uc11c\ub294 \uc5ec\uc131 \uc554\uc758 2.8%\uc815\ub3c4\ub97c \ucc28\uc9c0\ud558\uace0 \uc788\uc73c\uba70 \uc790\uad81\uacbd\ubd80\uc554\uc758 […]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[17104,2629,17102,642,17101,17105],"class_list":["post-11654","post","type-post","status-publish","format-standard","hentry","category-uncategorized","tag-17104","tag-2629","tag-17102","tag-642","tag-17101","tag-17105"],"_links":{"self":[{"href":"https:\/\/blog.agentsoft.co.kr\/index.php\/wp-json\/wp\/v2\/posts\/11654","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/blog.agentsoft.co.kr\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/blog.agentsoft.co.kr\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/blog.agentsoft.co.kr\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/blog.agentsoft.co.kr\/index.php\/wp-json\/wp\/v2\/comments?post=11654"}],"version-history":[{"count":0,"href":"https:\/\/blog.agentsoft.co.kr\/index.php\/wp-json\/wp\/v2\/posts\/11654\/revisions"}],"wp:attachment":[{"href":"https:\/\/blog.agentsoft.co.kr\/index.php\/wp-json\/wp\/v2\/media?parent=11654"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/blog.agentsoft.co.kr\/index.php\/wp-json\/wp\/v2\/categories?post=11654"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/blog.agentsoft.co.kr\/index.php\/wp-json\/wp\/v2\/tags?post=11654"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}