{"id":20382,"date":"2025-10-26T09:01:02","date_gmt":"2025-10-26T00:01:02","guid":{"rendered":"https:\/\/blog.agentsoft.co.kr\/index.php\/2025\/10\/26\/20382\/"},"modified":"2025-10-26T09:01:02","modified_gmt":"2025-10-26T00:01:02","slug":"wittig-horner-reaction","status":"publish","type":"post","link":"https:\/\/blog.agentsoft.co.kr\/index.php\/2025\/10\/26\/20382\/","title":{"rendered":"Wittig-Horner Reaction"},"content":{"rendered":"

<\/p>\n

\ubaa9\ucc28<\/strong><\/p>\n

1. Title
\n2. Purpose
\n3. Theory
\n4. Apparatus and Reagents
\n5. Procedure
\n6. Cautions
\n7. Data & Results
\n8. Discussion
\n9. Conclusion
\n10. References<\/p>\n

\ubcf8\ubb38\ub0b4\uc6a9<\/strong><\/p>\n

1. Title
\nWittig-Horner Reaction
\n2. Purpose
\nWittig reaction\uc758 \uc815\uc758\uc640 \uc7a5\uc810\uc744 \uc774\ud574\ud558\uace0, Wittig reagent\uc778 ylide\ub97c \uc9c1\uc811 \ud569\uc131\ud574 aldehyde\uc758 carbonyl\uc744 alkene\uc73c\ub85c \uc804\ud658\ud558\uace0 \uc0dd\uc131\ubb3c\uc744 \ubd84\uc11d\ud55c\ub2e4.
\n3. Theory
\n1) Wittig reaction & mechanism
\nWittig reaction\uc740 ketone\uc774\ub098 aldehyde\uc758 C=O \uacb0\ud569\uc744 \uc0c8\ub85c\uc6b4 C=C \uacb0\ud569\uc73c\ub85c \ubc14\uafb8\ub294 \ubc18\uc751\uc774\ub2e4. Witting reaction\uc5d0 \uc0ac\uc6a9\ub418\ub294 \uc2dc\uc57d\uc778 phosphorous ylide\ub294 \uc804\uccb4\uc801\uc73c\ub85c \uc804\ud558\ub97c \ub760\uc9c0 \uc54a\ub294 \ubd84\uc790\uc774\uc9c0\ub9cc, \ud0c4\uc18c\uac00 \ubd80\ubd84\uc801\uc73c\ub85c \uc74c\uc804\ud558\ub97c, \uc778\uc774 \ubd80\ubd84\uc801\uc73c\ub85c \uc591\uc804\ud558\ub97c \ub764\ub2e4. \uc774\ub54c \ud0c4\uc18c \uc74c\uc774\uc628\uc774 ketone\uc774\ub098 aldehyde\uc5d0 \ucca8\uac00\ub418\uc5b4 Wittig reaction\uc774 \uc77c\uc5b4\ub09c\ub2e4.
\nWittig reaction\uc5d0 \ud544\uc694\ud55c phosphorous ylide\uac00 \ub9cc\ub4e4\uc5b4\uc9c0\ub294 \uacfc\uc815\uc740 Figure 1\uacfc \uac19\ub2e4. \uba3c\uc800 alkyl halide\uc640 triphenylphosphine\uc774 SN2 \ubc18\uc751\uc744 \uac70\uce5c\ub2e4. \uc774\ub54c triphenylphosphine\uc758 \ubd80\ud53c\uac00 \ud06c\uae30 \ub54c\ubb38\uc5d0, steric hindrance\uac00 \uc791\uc740 1\ucc28 alkyl halide \ub610\ub294 methyl halide\uac00 \uc77c\ubc18\uc801\uc73c\ub85c \uc0ac\uc6a9\ub41c\ub2e4. 2\ucc28 alkyl halide\uc758 \uacbd\uc6b0 \ubc18\uc751\uc774 \uc9c4\ud589\ub420 \uc218 \uc788\uae30\ub294 \ud558\uc9c0\ub9cc, \uc18d\ub3c4\uac00 \ub290\ub9ac\uace0 \uc218\ub4dd\ub960\uc774 \ub0ae\ub2e4. \uc774\ud6c4 \uc0dd\uc131\ub41c phosphonium salt\ub97c butyllithium\uacfc \uac19\uc740 \uac15\ud55c \uc5fc\uae30\uc640 \ubc18\uc751\uc2dc\ucf1c phosphorous ylide\ub97c \uc5bb\ub294\ub2e4. \uc5bb\uc5b4\uc9c4 phosphorous ylide\ub294 2\uac1c\uc758 \uacf5\uba85 \uad6c\uc870\ub97c \uac16\ub294\ub2e4. \uc778\uacfc \ud0c4\uc18c\uac00 \uc774\uc911\uacb0\ud569\uc73c\ub85c \uc5f0\uacb0\ub41c \uad6c\uc870\ub294 \uc778\uc758 \uc6d0\uc790\uac00 \uaecd\uc9c8\uc5d0 10\uac1c\uc758 \uc804\uc790\uac00 \uc788\uc5b4\uc57c \ud558\uae30 \ub54c\ubb38\uc5d0 d \uc624\ube44\ud0c8\uc744 \uc0ac\uc6a9\ud55c\ub2e4. \uc774 \uad6c\uc870\ub294 \uc778\uacfc \ud0c4\uc18c \uc0ac\uc774\uc758 \uc57d\ud55c \ud30c\uc774 \uacb0\ud569\uc5d0 \uc758\ud574 \uc548\uc815\uc131\uc774 \ub5a8\uc5b4\uc9c0\ubbc0\ub85c, \ud0c4\uc18c\uc5d0\ub294 \uc74c\uc804\ud558, \uc778\uc5d0\ub294 \uc591\uc804\ud558\ub97c \ub764 \uad6c\uc870\uac00 \uacf5\uba85 \ud63c\uc131\uccb4\uc5d0 \ud070 \uae30\uc5ec\ub97c \ud558\uac8c \ub41c\ub2e4.
\nPhosphorous ylide\uac00 \uac00\uc9c4 \ud0c4\uc18c\uc758 \uc74c\uc804\ud558\ub85c \uc778\ud574 phosphorous ylide\ub294 \ud070 \uce5c\ud575\uc131\uc744 \uac00\uc9c4\ub2e4. \ub530\ub77c\uc11c phosphorous ylide\ub294 Wittig reaction\uc5d0\uc11c nucleophile\ub85c \uc791\uc6a9\ud558\uc5ec ketone\uc774\ub098 aldehyde\ub97c \uacf5\uaca9\ud55c\ub2e4. \uc544\ub798 \uc0ac\uc9c4\uc740 Wittig reaction\uc758 mechanism\uc744 \ub098\ud0c0\ub098\ub0b8\ub2e4.<\/p>\n

\ucd9c\ucc98 : \ud574\ud53c\ucea0\ud37c\uc2a4<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

\ubaa9\ucc28 1. Title 2. Purpose 3. Theory 4. Apparatus and Reagents 5. Procedure 6. Cautions 7. Data & Results 8. Discussion 9. Conclusion 10. References \ubcf8\ubb38\ub0b4\uc6a9 1. Title Wittig-Horner Reaction 2. Purpose Wittig reaction\uc758 \uc815\uc758\uc640 \uc7a5\uc810\uc744 \uc774\ud574\ud558\uace0, Wittig reagent\uc778 ylide\ub97c \uc9c1\uc811 \ud569\uc131\ud574 aldehyde\uc758 carbonyl\uc744 alkene\uc73c\ub85c \uc804\ud658\ud558\uace0 \uc0dd\uc131\ubb3c\uc744 \ubd84\uc11d\ud55c\ub2e4. 3. Theory 1) Wittig reaction & mechanism […]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[4195,11960,25197,15740,11936],"class_list":["post-20382","post","type-post","status-publish","format-standard","hentry","category-uncategorized","tag-a-","tag-wittig-reaction","tag-ylide","tag-15740","tag-11936"],"_links":{"self":[{"href":"https:\/\/blog.agentsoft.co.kr\/index.php\/wp-json\/wp\/v2\/posts\/20382","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/blog.agentsoft.co.kr\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/blog.agentsoft.co.kr\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/blog.agentsoft.co.kr\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/blog.agentsoft.co.kr\/index.php\/wp-json\/wp\/v2\/comments?post=20382"}],"version-history":[{"count":0,"href":"https:\/\/blog.agentsoft.co.kr\/index.php\/wp-json\/wp\/v2\/posts\/20382\/revisions"}],"wp:attachment":[{"href":"https:\/\/blog.agentsoft.co.kr\/index.php\/wp-json\/wp\/v2\/media?parent=20382"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/blog.agentsoft.co.kr\/index.php\/wp-json\/wp\/v2\/categories?post=20382"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/blog.agentsoft.co.kr\/index.php\/wp-json\/wp\/v2\/tags?post=20382"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}