{"id":21230,"date":"2025-11-04T09:00:08","date_gmt":"2025-11-04T00:00:08","guid":{"rendered":"https:\/\/blog.agentsoft.co.kr\/index.php\/2025\/11\/04\/21230\/"},"modified":"2025-11-04T09:00:08","modified_gmt":"2025-11-04T00:00:08","slug":"%ec%9c%a0%ea%b8%b0%ed%99%94%ed%95%99%ec%8b%a4%ed%97%982-prelab_-conjugate-michael-addition-to-a-b-unsaturated-carbonyl","status":"publish","type":"post","link":"https:\/\/blog.agentsoft.co.kr\/index.php\/2025\/11\/04\/21230\/","title":{"rendered":"\uc720\uae30\ud654\ud559\uc2e4\ud5d82 prelab_ Conjugate (Michael) Addition to a, b unsaturated Carbonyl"},"content":{"rendered":"

<\/p>\n

\ubaa9\ucc28<\/strong><\/p>\n

1. objectives
\n2. principle
\n3. methodes
\n4. expected result
\n5. table of relevant chemical properties
\n6. reference<\/p>\n

\ubcf8\ubb38\ub0b4\uc6a9<\/strong><\/p>\n

Objectives: Michael addition\uc758 \uacfc\uc815\uc744 \uc774\ud574\ud558\uace0, 1-Phenylmaleimide\uc5d0 PhNH2\ub97c \ubc18\uc751\uc2dc\ucf1c 1-Phenyl-3-phenylaminopyrrolidine-2,5-dione\uc744 \ud569\uc131\ud560 \uc218 \uc788\ub2e4.<\/p>\n

Principles:
\nNucleophilic enol anion\uc774 unsaturated carbonyl compound\uc640 \ubc18\uc751\ud574 \ub3d9\uc77c\ud55c \uc885\ub958\uc758 conjugation\ucca8\uac00 \ubc18\uc751\uc774 \uc77c\uc5b4\ub098\ub294 \uac83\uc744 Michael reaction\uc774\ub77c\uace0 \ud55c\ub2e4. \uc774\ub294 acidity\uac00 \ud074\uc218\ub85d, \uc785\uccb4\uc7a5\uc560\uac00 \uc801\uc744\uc218\ub85d \ube60\ub974\uac8c \uc77c\uc5b4\ub09c\ub2e4. \uc774 \ubc18\uc751\uc740 \uc5fc\uae30\uac00 \ucd09\ub9e4\ub85c \uc791\uc6a9\ud558\uc5ec \uc18c\ub7c9\ub9cc \uc4f0\uc774\uace0, \uac00\uc5ed\uc801\uc778 \ubc18\uc751\uc774\ub2e4. \ub610, pi bond\ub300\uc2e0 \uc0c8\ub85c\uc6b4 C-C single bond\uac00 \ud615\uc131\ub418\ub294 \uac83\uc5d0\uc11c \ubc18\uc751\uc774 \uc720\ub3c4\ub41c\ub2e4. \uadf8\ub9bc\uc758 machenism\uc5d0\uc11c \uc54c \uc218 \uc788\ub4ef, \uc2e4\ud5d8A\uc5d0\uc11c\ub294 maleic anhydride\uac00 aniline\uc640 acetic acid \uacfc \ubc18\uc751<\/p>\n

\ucd9c\ucc98 : \ud574\ud53c\ucea0\ud37c\uc2a4<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

\ubaa9\ucc28 1. objectives 2. principle 3. methodes 4. expected result 5. table of relevant chemical properties 6. reference \ubcf8\ubb38\ub0b4\uc6a9 Objectives: Michael addition\uc758 \uacfc\uc815\uc744 \uc774\ud574\ud558\uace0, 1-Phenylmaleimide\uc5d0 PhNH2\ub97c \ubc18\uc751\uc2dc\ucf1c 1-Phenyl-3-phenylaminopyrrolidine-2,5-dione\uc744 \ud569\uc131\ud560 \uc218 \uc788\ub2e4. Principles: Nucleophilic enol anion\uc774 unsaturated carbonyl compound\uc640 \ubc18\uc751\ud574 \ub3d9\uc77c\ud55c \uc885\ub958\uc758 conjugation\ucca8\uac00 \ubc18\uc751\uc774 \uc77c\uc5b4\ub098\ub294 \uac83\uc744 Michael reaction\uc774\ub77c\uace0 \ud55c\ub2e4. \uc774\ub294 acidity\uac00 \ud074\uc218\ub85d, \uc785\uccb4\uc7a5\uc560\uac00 \uc801\uc744\uc218\ub85d \ube60\ub974\uac8c \uc77c\uc5b4\ub09c\ub2e4. […]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[26014,26050,19140,2659,6907,4579,25987],"class_list":["post-21230","post","type-post","status-publish","format-standard","hentry","category-uncategorized","tag-chemistry","tag-conjugate","tag-lg","tag-report","tag-synthesis","tag-4579","tag-25987"],"_links":{"self":[{"href":"https:\/\/blog.agentsoft.co.kr\/index.php\/wp-json\/wp\/v2\/posts\/21230","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/blog.agentsoft.co.kr\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/blog.agentsoft.co.kr\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/blog.agentsoft.co.kr\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/blog.agentsoft.co.kr\/index.php\/wp-json\/wp\/v2\/comments?post=21230"}],"version-history":[{"count":0,"href":"https:\/\/blog.agentsoft.co.kr\/index.php\/wp-json\/wp\/v2\/posts\/21230\/revisions"}],"wp:attachment":[{"href":"https:\/\/blog.agentsoft.co.kr\/index.php\/wp-json\/wp\/v2\/media?parent=21230"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/blog.agentsoft.co.kr\/index.php\/wp-json\/wp\/v2\/categories?post=21230"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/blog.agentsoft.co.kr\/index.php\/wp-json\/wp\/v2\/tags?post=21230"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}