{"id":22841,"date":"2025-11-20T09:00:31","date_gmt":"2025-11-20T00:00:31","guid":{"rendered":"https:\/\/blog.agentsoft.co.kr\/index.php\/2025\/11\/20\/22841\/"},"modified":"2025-11-20T09:00:31","modified_gmt":"2025-11-20T00:00:31","slug":"%ec%84%b1%ec%9d%b8%ea%b0%84%ed%98%b8-%ec%8b%a4%ec%8a%b5-%ec%84%b1%ec%9d%b8%ea%b0%84%ed%98%b8-%ec%86%8c%ec%84%b8%ed%8f%ac-%ed%8f%90%ec%95%94-sclcsmall-cell-lung-cancer-%ec%bc%80%ec%9d%b4","status":"publish","type":"post","link":"https:\/\/blog.agentsoft.co.kr\/index.php\/2025\/11\/20\/22841\/","title":{"rendered":"[\uc131\uc778\uac04\ud638 \uc2e4\uc2b5, \uc131\uc778\uac04\ud638] \uc18c\uc138\ud3ec \ud3d0\uc554, SCLC(Small Cell Lung Cancer) \ucf00\uc774\uc2a4\uc2a4\ud130\ub514, \uac04\ud638\uc9c4\ub2e8, \uac04\ud638\uacfc\uc815 1\uac1c(\ube44\ud6a8\uacfc\uc801 \ud638\ud761\uc591\uc0c1, \uc2ec\ud638\ud761 \uad50\uc721\uc548 \ud3ec\ud568) + \ud56d\uc554 \uce58\ub8cc(\uc644\ud654 \uc694\ubc95) \uc804, \uc911, \ud6c4 \uac04\ud638"},"content":{"rendered":"

<\/p>\n

\ubaa9\ucc28<\/strong><\/p>\n

\u2160. \ubb38\ud5cc\uace0\ucc30\t 6<\/p>\n

\u2161. \ub300\uc0c1\uc790\uc758 \uc9c4\ub2e8\uc801 \uac80\uc0ac \ubc0f \uacb0\uacfc \ud574\uc11d\t 9<\/p>\n

\u2162. \ub300\uc0c1\uc790\uc758 \uc57d\ubb3c\uce58\ub8cc \ud604\ud669\t 12<\/p>\n

\u2163. \ub300\uc0c1\uc790\uc758 \uac04\ud638\ubb38\uc81c\t 18<\/p>\n

\u2164. \uc6b0\uc120\uc21c\uc704\uc5d0 \ub530\ub978 \ub300\uc0c1\uc790\uc758 \uac04\ud638\uc9c4\ub2e8 \ubaa9\ub85d\t 18<\/p>\n

\u2165. \uac04\ud638\uacfc\uc815\t 21
\n\u2165-1. \t 21
\n\u2165-2. \t28 <\/p>\n

\u2166. \ucc38\uace0 \ubb38\ud5cc\t 31<\/p>\n

\ubcf8\ubb38\ub0b4\uc6a9<\/strong><\/p>\n

I. \ubb38\ud5cc\uace0\ucc30<\/p>\n

1.\uc138\ud3ec\uc99d\uc2dd\uacfc \uc554\uc138\ud3ec
\n\uc778\uccb4 \ub0b4 \uc138\ud3ec\ub294 \uc131\uc7a5\uacfc \ubd84\uc5f4 \ubc0f \uc18c\uba78\uc744 \uc870\uc808\ud558\uba74\uc11c \uc138\ud3ec\uc218\uc758 \uade0\ud615\uc744 \uc720\uc9c0\ud55c\ub2e4. \uc5b4\ub5a4 \uc6d0\uc778\uc73c\ub85c \uc815\uc0c1\uc138\ud3ec\uac00 \uc190\uc0c1\uc744 \ubc1b\uac8c \ub418\uba74 \ub300\ubd80\ubd84\uc740 \ub2e4\uc2dc \ud68c\ubcf5\ud558\uc5ec \ubcf8\ub798\uc758 \uc5ed\ud560\uc744 \ud558\uba70, \uc815\uc0c1\uc138\ud3ec\ub85c \ud68c\ubcf5\ub418\uc9c0 \uc54a\uc73c\uba74 \uc18c\uba78\ud55c\ub2e4. \ud55c \uc138\ud3ec\uc758 \ud06c\uae30\uac00 \ucee4\uc9c0\ub294 \uac83\uc744 \ube44\ub300(hypertrophy)\ub77c \ud558\uace0, \uc138\ud3ec\uc758 \uc22b\uc790\uac00 \uc99d\uac00\ud558\uc5ec \uc870\uc9c1\uc774 \ucee4\uc9c0\ub294 \uac83\uc744 \uacfc\ud615\uc131(hyperplasia)\uc774\ub77c \ud55c\ub2e4.
\n\uc2e0\uc0dd\ubb3c(neoplasia)\uc740 \uc0c8\ub85c\uc6b4 \uc131\uc7a5\uc774\ub77c\ub294 \ub73b\uc73c\ub85c, \uc138\ud3ec\ubd84\uc5f4\uc744 \uc5b5\uc81c\uc2dc\ud0a4\ub294 \uc2e0\ud638\uac00 \uc5c6\uac70\ub098 \uc774 \uc2e0\ud638\uac00 \ubcc0\ud615\ub418\uc5b4 \uc138\ud3ec\uac00 \uacc4\uc18d\uc801\uc73c\ub85c \ubd84\uc5f4\ud558\uc5ec \uc99d\uac00\ud558\ub294 \uac83\uc774\ub2e4. \uc554\uc740 \uc544\uc9c1 \uadf8 \ubc1c\uc0dd\uc6d0\uc778\uacfc \uae30\uc804\uc774 \uc815\ud655\ud788 \ubc1d\ud600\uc838 \uc788\uc9c0 \uc54a\uace0 \uc0dd\ubb3c\ud559\uc801 \uc131\uc0c1\uc774 \ubcf5\uc7a1\ud558\uc5ec \uc815\uc758\ub97c \ub0b4\ub9ac\uae30\uac00 \uc5b4\ub824\uc6b0\ub098, \uc131\uc7a5\uacfc \ubd84\uc5f4\uc744 \uc870\uc808\ud558\ub294 \uc815\uc0c1\uc801\uc778 \ud1b5\uc81c\uae30\ub2a5\uc774 \uc18c\uc2e4\ub418\uace0, \ubb34\uc808\uc81c\ud55c \ubc29\uc2dd\uc73c\ub85c \uc138\ud3ec\uac00 \uacfc\ub3c4\ud558\uac8c \uc99d\uc2dd\ud558\ub294 \ud2b9\uc9d5\uc774 \uc788\ub2e4.
\n* \uc554(\uc545\uc131\uc885\uc591)\uc138\ud3ec\uc758 \ud2b9\uc131 : \uc9c0\uc18d\uc801\uc774\uba70 \ube60\ub978 \uc138\ud3ec\ubd84\uc5f4, \ubbf8\ubd84\ud654 \ud615\ud0dc, \ud575 \ube44\uc728 \uc99d\uac00, \ubd84\ud654\uae30\ub2a5 \uc0c1\uc2e4, \uc138\ud3ec\uc758 \uc751\uc9d1\ub825 \uc800\ud558, \uce68\uc2b5\u2022\uc804\uc774 \uac00\ub2a5, \uc811\ucd09\uc5b5\uc81c\uac00 \uc77c\uc5b4\ub098\uc9c0 \uc54a\uc74c, \uc815\ubc30\uc218\uccb4\uac00 \uc544\ub2d8<\/p>\n

2. \ubc1c\uc554\ud604\uc0c1
\n\ubc1c\uc554\ud604\uc0c1(carcinogenesis, oncogenesis)\uc774\ub098 \uc545\uc131\uc138\ud3ec\ub85c\uc758 \ubcc0\ud658\uacfc\uc815\uc740 3\ub2e8\uacc4(\ubc1c\ub2e8\uae30, \uc99d\uc9c4\uae30, \uc9c4\ud589\uae30) \uacfc\uc815\uc744 \ud1b5\ud558\uc5ec \uc774\ub8e8\uc5b4\uc9c4\ub2e4.
\n1) \ubc1c\ub2e8\uae30 Initiative period
\n\uc554 \ubc1c\uc0dd\uc758 \uccab \ubc88\uc9f8 \ub2e8\uacc4\ub85c\uc11c \ubc1c\uc554\ubb3c\uc9c8\uc778 \ud654\ud559\ubb3c\uc9c8, \uc0dd\ubb3c\ud559\uc801\u2022 \ubb3c\ub9ac\uc801 \uc778\uc790\uac00 \uc138\ud3ec \ub0b4 \ud575\uc73c\ub85c \ub4e4\uc5b4\uc640 DNA\uc758 \ubd84\uc790\uad6c\uc870\ub97c \ubc14\uafb8\uc5b4 \uc815\uc0c1\uc138\ud3ec\ub97c \uc554\uc138\ud3ec\ub85c \ubcc0\ud558\uac8c \ud55c\ub2e4. \uc21c\uc218 \ubc1c\uc554\ubb3c\uc9c8\uc740 \uc138\ud3ec\uc720\uc804\uc790\uc758 \ub3cc\uc5f0\ubcc0\uc774\ub97c \uc77c\uc73c\ud0a4\ub294\ub370, \uc774\ub97c \uac1c\uc2dc\uc790(initiator)\ub77c\uace0 \ubd80\ub978\ub2e4.
\n2) \uc99d\uc9c4\uae30 Promotional period
\n\uc815\uc0c1\uc138\ud3ec\uac00 \ubc1c\uc554\ubb3c\uc9c8\ub85c \uc778\ud574 \uc554\uc138\ud3ec\uc758 \ud2b9\uc131\uc744 \uac16\uac8c \ub418\uace0, \uc131\uc7a5\uc774 \ube68\ub77c\uc9c0\uba74 \uc885\uc591\uc744 \ud615\uc131\ud55c\ub2e4. \uc554\uc138\ud3ec \ubc1c\ub2e8\ubd80\ud130 \uba85\ubc31\ud55c \uc885\uc591\uc73c\ub85c \ubc1c\ub2ec\ud558\uae30\uae4c\uc9c0\uc758 \uae30\uac04\uc744 \uc7a0\ubcf5\uae30\ub77c\uace0 \ubd80\ub974\uba70, \uc218\uac1c\uc6d4\uc5d0\uc11c \uc218\ub144\uc774 \uac78\ub9b0\ub2e4. \ubc1c\ub2e8\uc774 \ub41c \uc138\ud3ec\uc758 \uc131\uc7a5\uc744 \ucd09\uc9c4\uc2dc\ud0a4\ub294 \ubb3c\uc9c8\uc744 \ucd09\uc9c4\uc790(promoter)\ub77c\uace0 \ud558\ub294\ub370, \uc5ec\uae30\uc5d0\ub294 \ud638\ub974\ubaac, \uc57d\ubb3c, \ud654\ud559\ubb3c\uc9c8 \ub4f1\uc774 \uc788\ub2e4.
\n3) \uc9c4\ud589\uae30 Progressive period
\n\uc554\uc774 1cm(\uc138\ud3ec 10\uc5b5 \uac1c)\ub85c \uc790\ub77c\uba74 \uac74\uac15\ubb38\uc81c\ub97c \uc720\ubc1c\ud55c\ub2e4. \ucd08\uae30\uc5d0\ub294 \ud655\uc0b0\uc5d0 \uc758\ud574 \uc885\uc591\uc758 \uc911\uc2ec\ubd80\uc704\uc5d0 \uc788\ub294 \uc138\ud3ec\uc5d0 \uc601\uc591\uc744 \uacf5\uae09\ud558\uc9c0\ub9cc\uff0c1cm \ud06c\uae30\uc758 \uc885\uc591\uc740 \ud655\uc0b0\ub9cc\uc73c\ub85c \uc911\uc559\ubd80\uc704\uae4c\uc9c0 \ud608\uc561\uc744 \uacf5\uae09\ud560 \uc218 \uc5c6\uc5b4 \uc790\uccb4 \ud608\uc561\uacf5\uae09\uccb4\uacc4\ub97c \uac16\ucd98\ub2e4. \uc885\uc591\uc740 \uc911\uc559\ubd80\uc704\ub85c \ud608\uc561\uc744 \uacf5\uae09\ud560 \uc218 \uc788\ub294 \uc885\uc591\ud608\uad00 \uc2e0\uc0dd\uc694\uc18c(tumor angiogenesis factor, TAF)\ub97c \ub9cc\ub4e0\ub2e4. TAF\ub294 \uc8fc\ubcc0\uc758 \ud608\uad00\uc744 \uc790\uadf9\ud558\uc5ec \uc885\uc591\uc5d0 \uc0c8\ub85c\uc6b4 \ud608\uad00\uc774 \ud615\uc131\ub418\ub3c4\ub85d \ud558\ub294 \ubb3c\uc9c8\uc774\ub2e4.<\/p>\n

\ucd9c\ucc98 : \ud574\ud53c\ucea0\ud37c\uc2a4<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

\ubaa9\ucc28 \u2160. \ubb38\ud5cc\uace0\ucc30 6 \u2161. \ub300\uc0c1\uc790\uc758 \uc9c4\ub2e8\uc801 \uac80\uc0ac \ubc0f \uacb0\uacfc \ud574\uc11d 9 \u2162. \ub300\uc0c1\uc790\uc758 \uc57d\ubb3c\uce58\ub8cc \ud604\ud669 12 \u2163. \ub300\uc0c1\uc790\uc758 \uac04\ud638\ubb38\uc81c 18 \u2164. \uc6b0\uc120\uc21c\uc704\uc5d0 \ub530\ub978 \ub300\uc0c1\uc790\uc758 \uac04\ud638\uc9c4\ub2e8 \ubaa9\ub85d 18 \u2165. \uac04\ud638\uacfc\uc815 21 \u2165-1. 21 \u2165-2. 28 \u2166. \ucc38\uace0 \ubb38\ud5cc 31 \ubcf8\ubb38\ub0b4\uc6a9 I. \ubb38\ud5cc\uace0\ucc30 1.\uc138\ud3ec\uc99d\uc2dd\uacfc \uc554\uc138\ud3ec \uc778\uccb4 \ub0b4 \uc138\ud3ec\ub294 \uc131\uc7a5\uacfc \ubd84\uc5f4 \ubc0f \uc18c\uba78\uc744 \uc870\uc808\ud558\uba74\uc11c \uc138\ud3ec\uc218\uc758 \uade0\ud615\uc744 \uc720\uc9c0\ud55c\ub2e4. […]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[9301,23958,25017,11626,20129,3559,20128,11262,28165],"class_list":["post-22841","post","type-post","status-publish","format-standard","hentry","category-uncategorized","tag-__aa","tag-23958","tag-a-","tag-lung-cancer-","tag-nsclc","tag-3559","tag-20128","tag-11262","tag-28165"],"_links":{"self":[{"href":"https:\/\/blog.agentsoft.co.kr\/index.php\/wp-json\/wp\/v2\/posts\/22841","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/blog.agentsoft.co.kr\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/blog.agentsoft.co.kr\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/blog.agentsoft.co.kr\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/blog.agentsoft.co.kr\/index.php\/wp-json\/wp\/v2\/comments?post=22841"}],"version-history":[{"count":0,"href":"https:\/\/blog.agentsoft.co.kr\/index.php\/wp-json\/wp\/v2\/posts\/22841\/revisions"}],"wp:attachment":[{"href":"https:\/\/blog.agentsoft.co.kr\/index.php\/wp-json\/wp\/v2\/media?parent=22841"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/blog.agentsoft.co.kr\/index.php\/wp-json\/wp\/v2\/categories?post=22841"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/blog.agentsoft.co.kr\/index.php\/wp-json\/wp\/v2\/tags?post=22841"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}