{"id":39053,"date":"2026-05-01T09:00:58","date_gmt":"2026-05-01T00:00:58","guid":{"rendered":"https:\/\/blog.agentsoft.co.kr\/index.php\/2026\/05\/01\/39053\/"},"modified":"2026-05-01T09:00:58","modified_gmt":"2026-05-01T00:00:58","slug":"28%eb%8f%84%ec%97%90%ec%84%9c%ec%9d%98-snc1-%eb%8b%a8%eb%b0%b1%ec%a7%88%ea%b3%bc-nup96%ec%9d%98-%ec%83%81%ea%b4%80%ea%b4%80%ea%b3%84","status":"publish","type":"post","link":"https:\/\/blog.agentsoft.co.kr\/index.php\/2026\/05\/01\/39053\/","title":{"rendered":"28\ub3c4\uc5d0\uc11c\uc758 SNC1 \ub2e8\ubc31\uc9c8\uacfc Nup96\uc758 \uc0c1\uad00\uad00\uacc4"},"content":{"rendered":"<p><img decoding=\"async\" src=\"https:\/\/image4.happycampus.com\/Production\/thumbnail\/2024\/06\/02\/data29957981-0001.jpg\"><img decoding=\"async\" src=\"https:\/\/image4.happycampus.com\/Production\/thumbnail\/2024\/06\/02\/data29957981-0002.jpg\"><\/p>\n<p><strong>\ubaa9\ucc28<\/strong><\/p>\n<p>\uc5c6\uc74c<\/p>\n<p><strong>\ubcf8\ubb38\ub0b4\uc6a9<\/strong><\/p>\n<p>\ubaa9\uc801: 22\ub3c4\uc5d0\uc11c SNC1\uc758 overexpression\uc740 autoimmunity\ub97c \uc720\ub3c4\ud588\uc9c0\ub9cc, 28\ub3c4\uc5d0\uc11c\ub294 \uadf8\ub807\uc9c0 \uc54a\uc558\ub2e4. 28\ub3c4\uc5d0\uc11c \ud575 \ub0b4\uc5d0 \uc704\uce58\ud558\ub294 SNC1 \ub2e8\ubc31\uc9c8\uc774 \uac10\uc18c\ud55c\ub2e4\ub294 \ubcf4\uace0\uac00 \uc788\uc5c8\ub2e4. \ud575\uacf5 \uc870\uc808 \ub2e8\ubc31\uc9c8\uc778 Nup96\uc774 \uc2dd\ubb3c \uba74\uc5ed \ubc18\uc751\uacfc \uc5f0\uad00\uc774 \uc788\ub2e4\ub294 \ubcf4\uace0\ub3c4 \uc788\uc5c8\ub2e4. \ub530\ub77c\uc11c 28\ub3c4\uc5d0\uc11c SNC1 \ub2e8\ubc31\uc9c8\uc774 Nup96\uc5d0 \uc758\ud574 \uc870\uc808\ub418\ub294\uc9c0\uc640 \uadf8 \ubc29\ubc95\uc744 \uc54c\uc544\ubcf8\ub2e4. (\ucd08\uae30 \uc628\ub3c4\ub97c 22\ub3c4, \ub530\ub4ef\ud55c \uc628\ub3c4\ub97c 28\ub3c4\ub85c \uc124\uc815\ud55c\ub2e4.)<\/p>\n<p>\uc2e4\ud5d8 \uc124\uacc41<br \/>\n\uc2e4\ud5d8 \ubaa9\uc801: 28\ub3c4\uc5d0\uc11c SNC1\uc758 \ud2b9\uc815 \ub2e8\ubc31\uc9c8 \ub3c4\uba54\uc778(TIR domain)\uc774 SNC1 \ub2e8\ubc31\uc9c8\uc758 cellular localization\uc5d0 \uae30\uc5ec \uc5ec\ubd80\uc640 \ubc29\ubc95\uc744 \uc870\uc0ac\ud55c\ub2e4. (TIR domain\uc744 \uc81c\uac70\ud55c SNC1\uc744 SNC1\u2019\uc774\ub77c\uace0 \uc124\uc815\ud55c\ub2e4.)<\/p>\n<p>\ucd9c\ucc98 : <a href=\"https:\/\/www.happycampus.com\/report-doc\/29957981\/\" target=\"_blank\">\ud574\ud53c\ucea0\ud37c\uc2a4<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>\ubaa9\ucc28 \uc5c6\uc74c \ubcf8\ubb38\ub0b4\uc6a9 \ubaa9\uc801: 22\ub3c4\uc5d0\uc11c SNC1\uc758 overexpression\uc740 autoimmunity\ub97c \uc720\ub3c4\ud588\uc9c0\ub9cc, 28\ub3c4\uc5d0\uc11c\ub294 \uadf8\ub807\uc9c0 \uc54a\uc558\ub2e4. 28\ub3c4\uc5d0\uc11c \ud575 \ub0b4\uc5d0 \uc704\uce58\ud558\ub294 SNC1 \ub2e8\ubc31\uc9c8\uc774 \uac10\uc18c\ud55c\ub2e4\ub294 \ubcf4\uace0\uac00 \uc788\uc5c8\ub2e4. \ud575\uacf5 \uc870\uc808 \ub2e8\ubc31\uc9c8\uc778 Nup96\uc774 \uc2dd\ubb3c \uba74\uc5ed \ubc18\uc751\uacfc \uc5f0\uad00\uc774 \uc788\ub2e4\ub294 \ubcf4\uace0\ub3c4 \uc788\uc5c8\ub2e4. \ub530\ub77c\uc11c 28\ub3c4\uc5d0\uc11c SNC1 \ub2e8\ubc31\uc9c8\uc774 Nup96\uc5d0 \uc758\ud574 \uc870\uc808\ub418\ub294\uc9c0\uc640 \uadf8 \ubc29\ubc95\uc744 \uc54c\uc544\ubcf8\ub2e4. (\ucd08\uae30 \uc628\ub3c4\ub97c 22\ub3c4, \ub530\ub4ef\ud55c \uc628\ub3c4\ub97c 28\ub3c4\ub85c \uc124\uc815\ud55c\ub2e4.) \uc2e4\ud5d8 \uc124\uacc41 \uc2e4\ud5d8 \ubaa9\uc801: 28\ub3c4\uc5d0\uc11c SNC1\uc758 [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[41810,48907,48908,31464,12392],"class_list":["post-39053","post","type-post","status-publish","format-standard","hentry","category-uncategorized","tag-41810","tag-48907","tag-48908","tag-31464","tag-12392"],"_links":{"self":[{"href":"https:\/\/blog.agentsoft.co.kr\/index.php\/wp-json\/wp\/v2\/posts\/39053","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/blog.agentsoft.co.kr\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/blog.agentsoft.co.kr\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/blog.agentsoft.co.kr\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/blog.agentsoft.co.kr\/index.php\/wp-json\/wp\/v2\/comments?post=39053"}],"version-history":[{"count":0,"href":"https:\/\/blog.agentsoft.co.kr\/index.php\/wp-json\/wp\/v2\/posts\/39053\/revisions"}],"wp:attachment":[{"href":"https:\/\/blog.agentsoft.co.kr\/index.php\/wp-json\/wp\/v2\/media?parent=39053"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/blog.agentsoft.co.kr\/index.php\/wp-json\/wp\/v2\/categories?post=39053"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/blog.agentsoft.co.kr\/index.php\/wp-json\/wp\/v2\/tags?post=39053"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}