Acute kidney injury 급성신부전

목차

1. INTRODUCTION
2. PATHOPHYSIOLOGY
3. CLINICAL FEATURES
4. DIAGNOSIS
5. TREATMENT
6. SPECIAL

본문내용

INTRODUCTION
Community-acquired AKI

Reversible mechanisms, such as volume depletion, medications, infection, or urinary obstruction
Mortality : from 7.3% to 19.6%

Hospital-acquired AKI
Occurs or worsens in the hospital
Mortality : from 27% to 62%

PATHOPHYSIOLOGY
Once the cause of injury is resolved, the remaining functional nephrons increase filtration and eventually hypertrophy

Vicious cycle

Remaining nephrons is below some critical number
Continued hyperfiltration results in progressive glomerular sclerosis
Leading to nephron loss

This sequence explains the commonly observed scenario in which progressive AKI occurs after
initial recovery from AKI, contributing to delayed mortality

출처 : 해피캠퍼스