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본문내용
Pharmacology Cardiovascular
1. Nurse Suspects that the client’s condition is Most likely related to the Abrupt discontinuation?
Beta-adrenergic antagonists=beta blockers (eg, metoprolol, atenolol)
심장의 beta-adrenergic receptors 에 대한 catecholamines (eg, epinephrine, norepinephrine) 작용 억제
> reduce cardiac workload > slows electrical conduction 전기 전도 through the heart > decreases HR and BP
treat hypertension, heart failure, anxiety 불안
Abrupt discontinuation
갑작스러운 중단
rebound hypertension 반동성 고혈압, angina, palpitations, myocardial infarction,
arrhythmias 부정맥 (eg, tachycardia, ventricular tachycardia) or sudden death
> 이러한 위험은 순환하는 catecholamines 에 대한 beta-adrenergic receptors 민감도 증가로
increased sympathetic response 교감신경 반응 증가하기 때문에 발생
Withdrawal symptoms resolve after resumption of the medication
출처 : 해피캠퍼스
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